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PDCD4 Polyclonal Antibody

CAT: 0763-E-AB-18246-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18246-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.
Abbreviation
PDCD4
UniProt
Q53EL6
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human PDCD4
Target
Death up-regulated gene protein; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor; Neoplastic transformation inhibitor protein; Nuclear antigen H731; Nuclear antigen H731 like; Nuclear antigen H731 like protein; Nuclear antigen H731-like; PDCD 4; Pdcd4; PDCD4; Programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor) ; Programmed cell death protein 4; Protein 197/15a; Protein MA-3; Tis; Topoisomerase-inhibitor suppressed protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q53EL6

Programmed cell death protein 4

PDCD4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q53EL6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PDCD4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RCV4, B5ME91, O15501, Q5VZS6, Q6PJI5, Q8TAR5, Q99834
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Cellular component

CytoplasmNucleus

Domain

Repeat

Molecular function

RNA-binding

Disease

Tumor suppressor

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