JAM3 Polyclonal Antibody

• Background:

  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  JAM3

• UniProt:

  Q9BX67

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human JAM3

• Target:

  FLJ14529; JAM 2 ; JAM 3; JAM C; JAM-2; JAM-3; JAM-C; JAM2 ; Jam3; JAM3; JAMC; Junctional adhesion molecule 3; Junctional adhesion molecule 3 precursor; Junctional adhesion molecule C

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cardiovascular; Signal Transduction; Tags; Cell Markers

• Purification:

  Antigen affinity purification

• Concentration:

  1.08 mg/mL

• Dilution:

  IHC 1:40-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG