COX6A2 Polyclonal Antibody

• Background:

  Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.

• Abbreviation:

  COX6A2

• UniProt:

  Q02221

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthetic peptide of human COX6A2

• Target:

  COX VIa M; COX6AH; COXVIAH; Cytochrome c oxidase polypeptide VIa heart; Cytochrome c oxidase subunit 6A2 mitochondrial; Cytochrome c oxidase subunit VIA muscle; Cytochrome c oxidase subunit VIa polypeptide 2; MS411

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Metabolism; Signal transduction

• Purification:

  Antigen affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  11 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG