COX6A2 Polyclonal Antibody

• Background:

  Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.

• Description:

  This is a COX6A2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  COX VIa M, COX6AH, COXVIAH, Cytochrome c oxidase polypeptide VIa heart, Cytochrome c oxidase subunit 6A2 mitochondrial, Cytochrome c oxidase subunit VIA muscle, Cytochrome c oxidase subunit VIa polypeptide 2, MS411

• Swiss Prot:

  Q02221

• Accession Number:

  NP005196

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human COX6A2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  11 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG