ECE2 Polyclonal Antibody

• Background:

  This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  ECE2

• UniProt:

  O60344

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Fusion protein of human ECE2

• Target:

  ECE 2; ECE-2; ECE2; ECE2; Endothelin converting enzyme 2; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; KIAA0604; MGC17664; MGC78487

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cardiovascular; Neuroscience; Signal transduction

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:500-2000; IHC 1:30-150

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  100 kDa

• Isotype:

  IgG