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SORT1 Polyclonal Antibody

CAT: 0763-E-AB-16874-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16874-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form.
Abbreviation
SORT1
UniProt
Q99523
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human SORT1
Target
100 kDa NT receptor; Glycoprotein 95; Gp 95; Gp95; LDLCQ6; Neurotensin receptor 3; NT 3; NT3; NTR 3; NTR3; OTTHUMP00000013784; SORT 1; SORT; SORT1 (gene name) ; Sort1; Sortilin 1; Sortilin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:40-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q99523

Sortilin

SORT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99523
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SORT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DWI3, C0JYZ0, Q8IZ49
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembraneNucleus

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinLipoproteinPalmitatePhosphoprotein

Molecular function

Developmental proteinReceptor

Biological process

DifferentiationEndocytosisOsteogenesisProtein transportTransport

Domain

RepeatSignalTransmembraneTransmembrane helix

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