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ARHGEF6 Polyclonal Antibody

CAT: 0763-E-AB-16170-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16170-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Abbreviation
ARHGEF6
UniProt
Q15052
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human ARHGEF6
Target
Alpha Pix; Alpha-Pix; ARHG6; ARHGEF6; COOL 2; COOL-2; COOL2; Mental retardation; X linked 46; MRX46; PAK interacting exchange factor alpha; PAK-interacting exchange factor alpha; PIXA; Rac/Cdc42 guanine exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor 6; Rho guanine nucleotide exchange factor 6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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