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SELENOS Polyclonal Antibody

CAT: 0763-E-AB-15863-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15863-02Size:60 µL
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Background
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Abbreviation
VIMP
UniProt
Q9BQE4
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human VIMP
Target
AD-015; ADO15; MGC104346; MGC2553; SBBI8; selenoprotein S; SEPS1; VCP interacting membrane protein; VCP-interacting membrane; VIMP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9BQE4

Selenoprotein S

SELS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BQE4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SELENOS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SelS
EC number
—
Processing
—
Secondary accessions
Q3B771, Q9P0I6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmEndoplasmic reticulumMembrane

PTM

PhosphoproteinUbl conjugation

Coding sequence diversity

Selenocysteine

Domain

TransmembraneTransmembrane helix

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