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Rabbit Polyclonal Antibody to SELENOS

CAT: 1725-P11131-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P11131-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER) . It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) . Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019) . [provided by RefSeq, Jul 2017]
Product Name Alternative
SELS; VIMP; ADO15; SBBI8; SEPS1; AD-015
Swiss Prot
Q9BQE4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human SELENOS
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
SELENOS

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