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PABPC1 Polyclonal Antibody

CAT: 0763-E-AB-15199-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15199-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
Abbreviation
PABPC1
UniProt
P11940
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PABPC1
Target
PAB 1; PAB1; PABP 1; PABP1; PABPC 1; PABPC1; PABPC2; PABPL1; Poly A binding protein 1; Poly A binding protein cytoplasmic 1; poly (A) binding protein; cytoplasmic 1; poly (A) binding protein; cytoplasmic 2; Polyadenylate binding protein 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71kDa
Isotype
IgG

UniProtKB · P11940

Polyadenylate-binding protein 1

PABP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11940
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PABPC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PABP-1, Poly(A)-binding protein 1
EC number
—
Processing
—
Secondary accessions
Q15097, Q93004
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cell projectionCytoplasmNucleusSpliceosome

Biological process

Host-virus interactionmRNA processingmRNA splicingNonsense-mediated mRNA decay

Domain

Repeat

Molecular function

RNA-binding

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