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FHL3 Polyclonal Antibody

CAT: 0763-E-AB-15038-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15038-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
FHL3
UniProt
Q13643
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human FHL3
Target
FHL 3; FHL-3; Fhl3; FHL3; Four and a half LIM domains 3; Four and a half LIM domains protein 3; Skeletal muscle LIM protein 2; Skeletal muscle LIM-protein 2; SLIM-2; SLIM2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell Markers
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q13643

Four and a half LIM domains protein 3

FHL3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13643
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FHL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FHL-3
EC number
—
Processing
—
Secondary accessions
D3DPT6, Q6I9T0, Q9BVA2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Acetylation

Molecular function

Activator

Cellular component

CytoplasmNucleus

Domain

LIM domainRepeatZinc-finger

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulation

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