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FHL1 Polyclonal Antibody

CAT: 0763-E-AB-15036-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15036-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
Abbreviation
FHL1
UniProt
Q13642
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human FHL1
Target
BA535K18.1; FHL 1; FHL 1B; FHL-1; FHL1; FHL1 protein; FHL1; FHL1A; FHL1B; FLH1A; Four and a half LIM domains 1; Four and a half LIM domains protein 1; Four and a half Lin11 Isl 1 and Mec 3 domains 1; four-and-a-half Lin11; Isl-1 and Mec-3; KYO T; KYOT; mouse; homolog of; LIM protein SLIMMER; MGC111107; RAM14-1; RBMX1A; RBMX1B; RBP associated molecule 14-1; RP11-535K18.1; Skeletal muscle LIM protein 1; Skeletal muscle LIM-protein 1; SLIM 1; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36kDa
Isotype
IgG

UniProtKB · Q13642

Four and a half LIM domains protein 1

FHL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13642
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FHL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FHL-1
EC number
—
Processing
—
Secondary accessions
B7Z5T4, B7Z793, O95212, Q13230, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental protein

Biological process

Differentiation

Disease

Disease variantEmery-Dreifuss muscular dystrophy

Domain

LIM domainRepeatZinc-finger

Ligand

Metal-bindingZinc