ASCC1 Polyclonal Antibody

• Background :

  This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF) . The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

• Abbreviation :

  ASCC1

• UniProt :

  Q8N9N2

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Recombinant protein of human ASCC1

• Target :

  Activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit p50; ASC1 complex subunit p50; ASC1p50; ASCC1; ASCC1; CGI 18; RP11-150D20.4; Trip4 complex subunit p50

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.3 mg/mL

• Dilution :

  IHC 1:25-1:100

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG