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ASCC1 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP06069-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06069-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1)| nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Synonyms
ASCC1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human ASCC1
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
44000
Antibody Type
Primary antibody
Isotype
IgG