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ALG2 Polyclonal Antibody

CAT: 0763-E-AB-14541-03Size: 120 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-14541-03Size:120 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2) GlcNAc (2) -dolichol diphosphate and Man (1) GlcNAc (2) -dolichol diphosphate to form Man (3) GlcNAc (2) -dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii) . Alternative splicing results in multiple transcript variants.
Abbreviation
ALG2
UniProt
Q9H553
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human ALG2
Target
3-mannosyltransferase ALG2; ALG2 alpha-1;3/1;6-mannosyltransferase; ALG2; ALG2; Alpha 1;3 mannosyltransferase ALG2; Alpha-1; Asparagine linked glycosylation protein 2; Asparagine-linked glycosylation protein 2 homolog; CDGIi; FLJ14511; GDP Man:Man (1) GlcNAc (2) PP dolichol mannosyltransferase; GDP-Man:Man (1) GlcNAc (2) -PP-dolichol mannosyltransferase; hALPG2; NET38; OTTHUMP00000021785; OTTHUMP00000123474; RP11-13B9.1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9H553

Alpha-1,3/1,6-mannosyltransferase ALG2

ALG2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H553
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ALG2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.1.132, 2.4.1.257
Processing
—
Secondary accessions
A2A2Y0, Q8NBX2, Q8NC39
Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Congenital disorder of glycosylationCongenital myasthenic syndromeDisease variant

Cellular component

Endoplasmic reticulumMembrane

Molecular function

GlycosyltransferaseTransferase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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