CAB39 Polyclonal Antibody

CAT: 0763-E-AB-13421-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-13421-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha) . STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK) .
Abbreviation
CAB39
UniProt
Q9Y376
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human CAB39
Target
Cab39; CAB39; Calcium binding protein 39; Calcium-binding protein 39; CGI 66; CGI-66; CGI66; MO25 alpha; MO25; Mouse protein 25 alpha; Protein Mo25
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
1.7 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40kDa
Isotype
IgG

Related Products

CatalogName
AN301743L-01Recombinant CAB39/MO25 Monoclonal Antibody
E-AB-14809-01CAB39L Polyclonal Antibody
E-AB-11016-01CAB39L Polyclonal Antibody
E-AB-65139-01Polyclonal AntibodyPC1 Polyclonal Antibody
AN100004PPAK1 Antibody Polyclonal Antibody
AN100005PCD44 Antibody Polyclonal Antibody
AN100003PPAK1 Antibody Polyclonal Antibody
E-AB-40332-01BBC3 Polyclonal Antibody
E-AB-40300-01EpCAM Polyclonal Antibody
D-AB-10260L-01PIK3CA Polyclonal Antibody

Alternative Products

CatalogName
MBS8570799-01CAB39 Polyclonal Antibody
TA371430CAB39 Rabbit Polyclonal Antibody
NBP1-55393Rabbit Polyclonal CAB39 Antibody
H00051719-B01PMouse Polyclonal CAB39 Antibody

Popular Products