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CEL Polyclonal Antibody

CAT: 0763-E-AB-13090-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-13090-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted.
Abbreviation
CEL
UniProt
P19835
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human CEL
Target
BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
79kDa
Isotype
IgG

UniProtKB · P19835

Bile salt-activated lipase

CEL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19835
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CEL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
BAL
EC number
3.1.1.13, 3.1.1.3, 3.1.1.6
Processing
Precursor
Secondary accessions
Q16398, Q5T7U7, Q9UCH1, Q9UP41
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseSerine esterase

Biological process

Lipid degradationLipid metabolism

Domain

RepeatSignal

Cellular component

Secreted