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ARAP1 Polyclonal Antibody

CAT: 0763-E-AB-12988-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12988-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) -dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
ARAP1
UniProt
Q96P48
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ARAP1
Target
2410002L19Rik; ANK repeat and PH domain-containing protein 1; ARAP 1; Arap1; ARAP1; Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1; Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1; Arf-GAP with Rho-GAP domain; CENT D2; Centaurin delta 2; Centaurin delta2; Centaurin-delta-2; CENTD 2; CENTD2; Cnt d2; Cnt-d2; Cntd2; KIAA0782; MGC176140; mKIAA0782
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96P48

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

ARAP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96P48
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ARAP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A3KLL7, B2RTS2, O94879, Q4LDD5, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCell projectionCytoplasmEndosomeGolgi apparatusMembrane

Molecular function

GTPase activation

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Domain

RepeatZinc-finger

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