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AMD1 Polyclonal Antibody

CAT: 0763-E-AB-12857-04Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12857-04Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.
Abbreviation
AMD1
UniProt
P17707
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human AMD1
Target
Adenosylmethionine decarboxylase 1; AdoMetDC; AMD1; DCAM; EC 4.1.1.50; FLJ26964; S adenosylmethionine decarboxylase 1; S adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase beta chain; SAMDC
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P17707

S-adenosylmethionine decarboxylase proenzyme

DCAM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17707
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AMD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AdoMetDC, SAMDC
EC number
4.1.1.50
Processing
Precursor
Secondary accessions
E1P5F7, Q5VXN4, Q5VXN6, Q9BWK4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Autocatalytic cleavagePhosphoproteinZymogen

Molecular function

DecarboxylaseLyase

Biological process

Polyamine biosynthesisSpermidine biosynthesis

Ligand

PyruvateS-adenosyl-L-methionineSchiff base

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