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FADS1 Polyclonal Antibody

CAT: 0763-E-AB-11209-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11209-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
Abbreviation
FADS1
UniProt
O60427
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human FADS1
Target
D5D; Delta 5 desaturase; Delta 5 fatty acid desaturase; Delta (5) desaturase; Delta (5) fatty acid desaturase; Delta-5 desaturase; Fads1; FADS1; FADS6; FADSD5; Fatty acid desaturase 1; FLJ38956; Linoleoyl CoA desaturase (delta 6 desaturase) like 1; LLCDL1; TU12
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction; Tags and Cell Markers
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52kDa
Isotype
IgG

UniProtKB · O60427

Acyl-CoA (8-3)-desaturase

FADS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60427
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FADS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.19.44
Processing
—
Secondary accessions
A8K0I7, B2RAI0, Q53GM5, Q8N3A6, Q8NCC7, Q8NCG0, Q96I39, Q96SV3, Q96T10, Q9NRP8, Q9NYX1
Protein keywords

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Biological process

Electron transportFatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolismTransport

Cellular component

Endoplasmic reticulumMembraneMitochondrion

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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