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DACH2 Polyclonal Antibody

CAT: 0763-E-AB-11136-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11136-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
DACH2
UniProt
Q96NX9
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human DACH2
Target
DACH 2; Dach2; DACH2; Dachshund 2; Dachshund homolog 2 (Drosophila) ; Dachshund homolog 2; Dachshund2; FLJ31391 ; HGNC:16814; MGC138545
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96NX9

Dachshund homolog 2

DACH2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96NX9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DACH2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dach2
EC number
—
Processing
—
Secondary accessions
B1AJV3, B4DQG3, Q8NAY3, Q8ND17, Q96N55
Protein keywords

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Molecular function

Developmental proteinDNA-bindingRepressor

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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