M-CSF-γ (human, recombinant)

• Description:

  M-CSF-γ (human, recombinant)_x000D_ Catalog number: B2017319_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 18.4 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’80°C_x000D_ Keywords: CSF-1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Hume DA, MacDonald KP. Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling Blood. 2012 Feb 23;119(8):1810-20._x000D_ 2: Ushach I, Zlotnik A. Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage J Leukoc Biol. 2016 Sep;100(3):481-9._x000D_ 3: Sehgal A, Irvine KM, Hume DA. Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair Semin Immunol. 2021 Apr;54:101509._x000D_ 4: Elmore MR, Najafi AR, Koike MA, Dagher NN, Spangenberg EE, Rice RA, Kitazawa M, Matusow B, Nguyen H, West BL, Green KN. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain Neuron. 2014 Apr 16;82(2):380-97._x000D_ 5: Chockalingam S, Ghosh SS. Macrophage colony-stimulating factor and cancer: a review Tumour Biol. 2014 Nov;35(11):10635-44._x000D_ 6: Yadav S, Priya A, Borade DR, Agrawal-Rajput R. Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance Immunol Res. 2023 Apr;71(2):130-152._x000D_ 7: Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan AB, Abow AA, Schroer SA, Hyduk SJ, Althagafi MG, McKee TD, Fu F, Shabro S, Ulndreaj A, Chiu F, Paneda E, Pacheco S, Wang T, Li A, Jiang JX, Libby P, Husain M, Wang B, Rubin BB, Cybulsky MI, Robbins CS. Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche Immunity. 2022 May 10;55(5):862-878.e8._x000D_ 8: Kager M, Kager R, FaÅ‚ek P, FaÅ‚ek A, Szczypiór G, Niemunis-Sawicka J, Rzepecka-Wejs L, StarosÅ‚awska E, Burdan F. Tenosynovial giant cell tumor Folia Med Cracov. 2022;62(2):93-107._x000D_ 9: Fixe P, Praloran V. Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships Eur Cytokine Netw. 1997 Jun;8(2):125-36._x000D_ 10: Keshvari S, Genz B, Teakle N, Caruso M, Cestari MF, Patkar OL, Tse BWC, Sokolowski KA, Ebersbach H, Jascur J, MacDonald KPA, Miller G, Ramm GA, Pettit AR, Clouston AD, Powell EE, Hume DA, Irvine KM. Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease Dis Model Mech. 2022 Apr 1;15(4):dmm049387. _x000D_ _x000D_ Products Related to M-CSF-γ (human, recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2017319 (20 µg)_x000D_ M-CSF-γ (human, recombinant) is a form of Macrophage Colony-Stimulating Factor produced using recombinant DNA technology. It is a cytokine crucial for the survival, proliferation, and differentiation of hematopoietic precursor cells into macrophages. The "γ" designation refers to a specific isoform. It is used in research on immune response, inflammation, and hematopoiesis. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3