Recombinant Murine GM-CSF

• Short Description:

  Catalog Number: B2017211 (5 µg)_x000D_ Recombinant Murine GM-CSF is a high quality Recombinant GM-CSF, a cytokine, a type of signaling molecule that plays a crucial role in the immune system by stimulating the production and differentiation of white blood cells, particularly granulocytes and macrophages. These cells are essential for the body's defense against infections and for the regulation of immune responses. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Description:

  Recombinant Murine GM-CSF_x000D_ Catalog number: B2017211_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 µg_x000D_ Molecular Weight or Concentration: 15.1 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Tu F, Pan L, Wu W, Cai Y, Li J, Wang X, Lai X, Chen Z, Ye L, Wang S. Recombinant GM-CSF enhances the bactericidal ability of PMNs by increasing intracellular IL-1β and improves the prognosis of secondary Pseudomonas aeruginosa pneumonia in sepsis J Leukoc Biol. 2023 Oct 26;114(5):443-458._x000D_ 2: Wiltschke C, Nemet H, Holzinger C, Gessl A, Pernerstorfer T, Förster O, Boltz-Nitulescu G. Murine recombinant GM-CSF-driven rat bone marrow cell differentiation and factors suppressing cell proliferation Immunobiology. 1989 Jun;179(2-3):145-58._x000D_ 3: Robinson EK, Covarrubias S, Zhou S, Carpenter S. Generation and utilization of a HEK-293T murine GM-CSF expressing cell line PLoS One. 2021 Apr 9;16(4):e0249117._x000D_ 4: Zhan Y, Vega-Ramos J, Carrington EM, Villadangos JA, Lew AM, Xu Y. The inflammatory cytokine, GM-CSF, alters the developmental outcome of murine dendritic cells Eur J Immunol. 2012 Nov;42(11):2889-900._x000D_ 5: Yeapuri P, Olson KE, Lu Y, Abdelmoaty MM, Namminga KL, Markovic M, Machhi J, Mosley RL, Gendelman HE. Development of an extended half-life GM-CSF fusion protein for Parkinson's disease J Control Release. 2022 Aug;348:951-965._x000D_ 6: Corcoran LM, Metcalf D, Edwards SJ, Handman E. GM-CSF produced by recombinant vaccinia virus or in GM-CSF transgenic mice has no effect in vivo on murine cutaneous leishmaniasis J Parasitol. 1988 Oct;74(5):763-7._x000D_ 7: Evans R, Shultz LD, Dranoff G, Fuller JA, Kamdar SJ. CSF-1 regulation of Il6 gene expression by murine macrophages: a pivotal role for GM-CSF J Leukoc Biol. 1998 Dec;64(6):810-6._x000D_ 8: Gao J, Huang S, Li M, Luo R, Wang X, Takashima A. GM-CSF-surface-modified B16.F10 melanoma cell vaccine Vaccine. 2006 Jun 19;24(25):5265-8._x000D_ 9: Withoff S, Glazenburg KL, van Veen ML, Kraak MM, Hospers GA, Störkel S, de Vries EG, Wilschut J, Daemen T. Replication-defective recombinant Semliki Forest virus encoding GM-CSF as a vector system for rapid and facile generation of autologous human tumor cell vaccines Gene Ther. 2001 Oct;8(20):1515-23._x000D_ 10: Van Dis E, Fox DM, Morrison HM, Fines DM, Babirye JP, McCann LH, Rawal S, Cox JS, Stanley SA. IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α PLoS Pathog. 2022 Jul 25;18(7):e1010721. _x000D_ _x000D_ Products Related to Recombinant Murine GM-CSF can be found at Proteins

• CAS Number:

  9000-83-3

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5