GC-IN-2

• Description:

  GC-IN-2 (Compound 25) is a potent, selective, and nonsugar glucocerebrosidase inhibitor with an IC50 of 6.46 μM. GC-IN-2 can be utilized in research related to Gaucher disease[1].

• UNSPSC:

  12352005

• Target:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/gc-in-2.html

• Smiles:

  O=C(NC1=CC=CC=C1)C2=CC=C(NS(=O)(C3=CC=CC=C3)=O)C=C2

• Molecular Formula:

  C19H16N2O3S

• Molecular Weight:

  352.41

• References & Citations:

  [1]Zheng W, et al. Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. Proc Natl Acad Sci U S A. 2007 Aug 7;104 (32) :13192-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [333441-43-3]