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APP (Phospho-Y757) Antibody Blocking peptide

CAT: 0013-GTR18969681Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18969681Size:500 µg
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Description
APP (Phospho-Y757) Antibody Blocking peptide
Product Name Alternative
Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3 (42), P3 (40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID (59), Gamma-CTF (59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID (57), Gamma-CTF (57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID (50), Gamma-CTF (50), C31, APP, A4, AD1
UniProt
P05067
Field of Research
Cell Biology
Form
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Notes
For research use only.
Applications Notes
Synthetic peptide
AA Sequence
The synthetic peptide sequence was selected from the region of human Phospho-APP-Y757. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APP
EC number
—
Processing
Precursor
Secondary accessions
B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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