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Lipid 14

CAT: 0804-HY-153377-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153377-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipid 14 is an ionizable amino lipid. Lipid 14 delivers mRNA into target cells, significantly enhancing the in vivo expression efficiency and immunogenicity of mRNA. Lipid 14 can be used to synthesize lipid nanoparticles (LNPs) . Lipid 14 can be used for studies of SARS-CoV-2 and Yersinia pestis[1][2].
CAS Number
2430034-05-0
UNSPSC
12352211
Target
Bacterial; Liposome; SARS-CoV
Type
Oligonucleotides
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lipid-14.html
Concentration
10mM
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCN(C)C)OCCN(CCCCCCCCOC(C(CCCCCCCC)CCCCCC)=O)CCCCCCCCOC(C(CCCCCCCC)CCCCCC)=O
Molecular Formula
C56H110N2O6
Molecular Weight
907.48
References & Citations
[1]Elia U, et al. Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles. ACS Nano. 2021 Jun 22;15 (6) :9627-9637.|[2]Kon E, et al. A single-dose F1-based mRNA-LNP vaccine provides protection against the lethal plague bacterium. Sci Adv. 2023 Mar 10;9 (10) :eadg1036.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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