Lipid I97

• Description :

  Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23) . Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines[1].

• UNSPSC :

  12352211

• Target :

  Liposome

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer; Inflammation/Immunology

• Smiles :

  CCCCCCCCC(CCCCCC)COC(CCCC(OCC(C)(C)[C@H](C(NCCC(OCCN(C)C)=O)=O)OC(CCCC(OCC(CCCCCC)CCCCCCCC)=O)=O)=O)=O

• Molecular Formula :

  C55H102N2O11

• Molecular Weight :

  967.41

• References & Citations :

  [1]Yoo S, et al., Novel Less Toxic, Lymphoid Tissue-Targeted Lipid Nanoparticles Containing a Vitamin B5-Derived Ionizable Lipid for mRNA Vaccine Delivery. Adv Healthc Mater. 2025 Mar;14 (7) :e2403366.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3046404-81-0]