8(S),9(R)-EET

CAT:

804-HY-150092

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CAS Number: 123931-39-5
UNSPSC Description: 8(S),9(R)-EET is an eicosanoid product of Arachidonic acid (AA; HY-109590) by cytochromes P450. 8(S),9(R)-EET dilates canine epicardial arterioles in a concentration-dependent manner with an EC50 value of 121 nM[1][2].
Target Antigen: Drug Metabolite
Type: Natural Products
Related Pathways: Metabolic Enzyme/Protease
Applications: Neuroscience-Neuromodulation
Field of Research: Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/8-s-9-r-eet.html
Smiles: CCCCC/C=C\C/C=C\C[C@@H]1[C@@H](O1)C/C=C\CCCC(O)=O
Molecular Weight: 320.47
References & Citations: [1]D C Zeldin, et al. Epoxygenase pathways of arachidonic acid metabolism. J Biol Chem. 2001 Sep 28;276(39):36059-62.|[2]Y Zhang, et al. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels. Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2430-40.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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