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7-Ethoxycoumarin

CAT: 0804-HY-133091-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133091-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin.
CAS Number
31005-02-4
Product Name Alternative
7-O-Ethylumbelliferone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/7-ethoxycoumarin.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=CC=C(OCC)C=C2O1
Molecular Formula
C11H10O3
Molecular Weight
190.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim DH, et al. Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3. Drug Metab Dispos. 2008 Nov;36 (11) :2166-70.|[2]Steensma A, et al. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices. Xenobiotica. 1994 Sep;24 (9) :893-907.|[3]Coomes MW, et al. Oxidation of 7-ethoxycoumarin and conjugation of umbelliferone by intact, viable epidermal cells from the hairless mouse. J Invest Dermatol. 1984 Jun;82 (6) :598-601.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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