Anti-Splicing factor 3B subunit 2 SF3B2 Antibody

• Description:

  Boster Bio Anti-Splicing factor 3B subunit 2 SF3B2 Antibody catalog # A07047. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Splicing factor 3B subunit 2; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SF3b145; Spliceosome-associated protein 145; SAP 145; SF3B2; SAP145;

• Gene Name:

  SF3B2

• UniProt:

  Q13435

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human SF3B2 (NP_006833.2) .

• Clonality:

  Polyclonal

• Applications:

  WB, IHC, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643) . SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937) . May also be involved in the assembly of the 'E' complex (PubMed:10882114) . Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077) .

• Molecular Weight:

  100228 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Splicing factor 3B subunit 2

• Subcellular Location:

  Nucleus

• Protein Name:

  Splicing factor 3B subunit 2