Mouse E-Cadherin PicoKine® Quick ELISA Kit

Mouse E-Cadherin PicoKine® Quick ELISA Kit

• Background: E-Cadherin, also called Cadherin 1 (CDH1), Uvomorulin or calcium-dependent ashesion protein, epithelial. E-cadherin is a Ca (2+)-dependent epithelial cell-cell adhesion molecule. Downregulation of E-cadherin expression often correlates with strong invasive potential and poor prognosis of human carcinomas. The gene spans a region of approximately 100 kb, and its location on chromosome 16q22.1. It contains 16 exons and a 65-kb-long intron 2. E-cadherin gene mutations may contribute to the development of diffusely growing gastric carcinomas. E-cadherin plays a central part in the process of epithelial morphogenesis and acts as a strong invasion suppressor in experimental tumor cell systems.
• Description: Mouse E-Cadherin 1 PicoKine® Quick ELISA Kit (120 minutes, 96 Tests). Quantitate Mouse Cdh1 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 15pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Cadherin-1;ARC-1;Epithelial cadherin;E-cadherin;Uvomorulin;CD324;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;Cdh1;
• Gene Name: Cadherin-1
• Gene ID: 12550
• UniProt: P09803
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: D157-V709
• Applications: ELISA
• Sample Type: cell culture supernatants, serum and plasma (heparin).
• Detection Range: 156 pg/ml - 10,000 pg/ml
• Sensitivity: <15 pg/ml
• Storage Conditions: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)
• Specificity: Natural and recombinant mouse E-Cadherin
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	242	247	246	242	244	2.27	0.9%
  Sample 2	1644	1884	1788	1601	1729	113.04	6.5%
  Sample 3	5631	5520	5145	4973	5317	268.19	5%

  *number of samples for each test n=16.
• : heparin
• Calculated Molecular Weight: 98256 MW