APP-018

• UNSPSC Description:

  APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases[1].

• Target Antigen:

  Apolipoprotein

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/app-018.html

• Smiles:

  C([C@H](C(N[C@H](CC1=CC=CC=C1)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC4=CC=CC=C4)C(N)=O)=O)C)=O)CCC(O)=O)=O)CCCCN)=O)=O)CCCCN)=O)CCC(O)=O)=O)C)=O)C(C)C)=O)CCCCN)=O)CC(O)=O)=O)=O)CC5=CC=CC=C5)=O)C)=O)CCCCN)=O)=O)NC([C@@H](CC(O)=O)NC(C)=O)=O)C=6C=7C(NC6)=CC=CC7

• Molecular Weight:

  2310.60

• References & Citations:

  [1]Bloedon LT, et al., Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients. J Lipid Res. 2008 Jun;49(6):1344-52.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  452782-06-8