BCN-OH
CAT:
804-HY-W111141-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BCN-OH
- CAS Number: 1263166-90-0
- UNSPSC Description: BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is a mitochondrial probe based on the lyophilic bidentate bicyclic ligand BCN and is a control reagent for BCN-TPP. The TPP group is a reactive sulfenic acid probe that targets mitochondria. BCN-TPP is known to affect mitochondrial energy, causing a sharp decrease in basal respiration, causing it to exhibit faster reaction kinetics with sulfonated proteins. BCN-OH does not contain hydrophobic triphenylphosphonium (TPP) ions. Using BCN-OH as a control allows the TPP group to be safely introduced when designing sulfenic acid traps[1].
- Target Antigen: Biochemical Assay Reagents
- Type: Biochemical Assay Reagents
- Related Pathways: Others
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/bcn-oh.html
- Purity: 99.40
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: [H][C@]12[C@@]([H])([C@@H]2CO)CCC#CCC1
- Molecular Weight: 150.22
- References & Citations: [1]Li Z, et al. Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function. Chem Res Toxicol. 2019 Mar 18;32(3):526-534.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported