PROTAC SMARCA2/4-degrader-30

PROTAC SMARCA2/4-degrader-30

• CAS Number: 2568276-44-6
• UNSPSC Description: PROTAC SMARCA2/4-degrader-30 (Compound I-291) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-30 degrades SMARCA2 in A549 and in MV411 with DC50 SMARCA4 in MV411 with DC50 [1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-smarca2-4-degrader-30.html
• Smiles: OC1=CC=CC=C1C2=CC(N3CC4CCC(N4C5=NC=C(C6CCN([C@H]7CC[C@H](C8=CC(N(C)C(N9C%10CCC(NC%10=O)=O)=O)=C9C=C8)CC7)CC6)C=N5)C3)=C(N)N=N2
• Molecular Weight: 797.95
• References & Citations: [1]Ji N, et al., Smarca degraders and uses thereof. US20230072658A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported