Lenalidomide-ethyne-C2-Pip-CO-Pip

CAT:

804-HY-170319

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UNSPSC Description: Lenalidomide-ethyne-C2-Pip-CO-Pip (intermediate 3) is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). Lenalidomide-ethyne-C2-Pip-CO-Pip can be used to synthesize QA-68 (HY-150797)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/lenalidomide-ethyne-c2-pip-co-pip.html
Smiles: O=C1C2=C(CN1C(C3=O)CCC(N3)=O)C(C#CCCN4CCN(CC4)C(N5CCNCC5)=O)=CC=C2
Molecular Weight: 492.57
References & Citations: [1]Weisberg E, et al. BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood Cancer J. 2022 Jul 19;12(7):110.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-170319	Lenalidomide-ethyne-C2-Pip-CO-Pip
HY-170315	Ethyne-C2-Pip-CO-Pip-Boc
HY-159618	(3S)Lenalidomide-5-Pip-C-Pip-2C-Pip
HY-169362	Lenalidomide-Pip-butyn
HY-168723	Piperidine-C-Pip-C2-Pip-C2-OH
HY-168298	Lenalidomide-6-F-piperidine-C2-Pip-C-COOH
HY-168724	Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH
HY-159617	Cbz-Pip-2C-Pip-C-Pip
HY-168297	Piperidine-C2-Pip-C-COOH
HY-163963	IBT6A-CO-ethyne

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