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PAI-1 Recombinant Protein

CAT: 0013-GTR18911807-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18911807-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAI-1 Recombinant Protein
Product Name Alternative
PAI, PAI1, PAI-1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, PAI
UniProt
P05121
Source
E. coli
Field of Research
Cancer Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 ̊C. Half maximal inhibition against 1.0 μg/mL of single chain tPA was obtained at a concentration of 2.0 μg/mL.
Form
Lyophilized
Storage Conditions
The lyophilized PAI-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted PAI-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing PAI-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_000593.1
AA Sequence
MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGV ASVLAMLQLT TGGETQQQIQ AAMGFKIDDK GMAPALRHLY KELMGPWNKD EISTTDAIFV QRDLKLVQGF MPHFFRLFRS TVKQVDFSEV ERARFIINDW VKTHTKGMIS NLLGKGAVDQ LTRLVLVNAL YFNGQWKTPF PDSSTHRRLF HKSDGSTVSV PMMAQTNKFN YTEFTTPDGH YYDILELPYH GDTLSMFIAA PYEKEVPLSA LTNILSAQLI SHWKGNMTRL PRLLVLPKFS LETEVDLRKP LENLGMTDMF RQFQADFTSL SDQEPLHVAQ ALQKVKIEVN ESGTVASSST AVIVSARMAP EEIIMDRPFL FVVRHNPTGT VLFMGQVMEP

UniProtKB · P05121

Plasminogen activator inhibitor 1

PAI1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05121
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PAI, PAI-1
EC number
—
Processing
Precursor
Secondary accessions
B7Z4S0, F8WD53
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Glycoprotein

Molecular function

Protease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

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