Pomalidomide-PEG1-NH2 (hydrochloride)
CAT:
804-HY-136772-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pomalidomide-PEG1-NH2 (hydrochloride)
- CAS Number: 2380273-67-4
- UNSPSC Description: Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/pomalidomide-peg1-nh2-1-hydrochloride.html
- Smiles: [H]Cl.NCCOCC(NC1=CC=CC(C2=O)=C1C(N2C(C3=O)CCC(N3)=O)=O)=O
- Molecular Weight: 410.81
- References & Citations: [1]Lee B, et al. Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66.
- Shipping Conditions: Blue Ice