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Pomalidomide-C7-NH2 (hydrochloride)

CAT:
804-HY-131878-05
Size:
100 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Pomalidomide-C7-NH2 (hydrochloride) - image 1

Pomalidomide-C7-NH2 (hydrochloride)

  • Product Name Alternative: Pomalidomide 4'-alkylC7-amine (hydrochloride)
  • CAS Number: 2446474-05-9
  • UNSPSC Description: Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].
  • Target Antigen: E3 Ligase Ligand-Linker Conjugates
  • Type: Reference compound
  • Related Pathways: PROTAC
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/pomalidomide-c7-nh2-hydrochloride.html
  • Purity: 98.98
  • Solubility: DMSO : 125 mg/mL (ultrasonic)
  • Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCN)=O.[H]Cl
  • Molecular Weight: 422.91
  • References & Citations: [1]Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.|[2]Si Woo Choi, et al. Hmg-coa reductase degradation inducing compound. Patent, WO2021201577A1.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
  • Clinical Information: No Development Reported