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NFAT Inhibitor-3

CAT: 0804-HY-132243Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-132243Size:1 Each
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Description
NFAT Inhibitor-3 (Compound 10) is a factor nuclear factor of activated T cells (NFAT) inhibitor. NFAT Inhibitor-3 inhibits IL-2 production. NFAT Inhibitor-3 binds in a sequence-selective manner directly to DNA. NFAT Inhibitor-3 can be used for the research of transcription factor dysregulation[1].
CAS Number
841210-82-0
UNSPSC
12352005
Target
Nuclear Factor of activated T Cells (NFAT)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nfat-inhibitor-3.html
Smiles
O=C(C)NC1=CC=CC(NC(CSC2=CC=C(C3=NC4=CC=CC=C4N3)C=N2)=O)=C1
Molecular Formula
C22H19N5O2S
Molecular Weight
417.48
References & Citations
[1]Mognol GP, et al. Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor. Proc Natl Acad Sci U S A. 2019 May 14;116 (20) :9959-9968.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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