Microtubule inhibitor 3
CAT:
804-HY-147724
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Microtubule inhibitor 3
- CAS Number: 1236141-96-0
- UNSPSC Description: Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
- Target Antigen: Microtubule/Tubulin
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/microtubule-inhibitor-3.html
- Solubility: 10 mM in DMSO
- Smiles: CC(C)(C1=C(N=CN1)/C=C2NC(/C(NC\2=O)=C/C3=CC(C(C4=CC=C(C=C4)F)=O)=CC=C3)=O)C
- Molecular Weight: 458.48
- References & Citations: [1]Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported