Amantadine-d15 (hydrochloride)

Amantadine-d15 (hydrochloride)

• UNSPSC Description: Amantadine-d15 hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research[1][2][3][4][5][6].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Infection; Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: NC1(C([2H])([C@@]2(C([2H])([C@]([2H])(C1([2H])[2H])C([2H])([C@]3(C2([2H])[2H])[2H])[2H])[2H])[2H])[2H])C3([2H])[2H].Cl
• Molecular Weight: 202.80
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported