7-epi-Isogarcinol

• UNSPSC Description:

  7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration[1].

• Target Antigen:

  Apoptosis; STAT

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/7-epi-isogarcinol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)\C)C)=C(C([C@@]1(C(C)([C@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)C(C4=CC(O)=C(C=C4)O)=O

• Molecular Weight:

  602.80

• References & Citations:

  [1]Xu ZH, et al. Polycyclic Polyprenylated Acylphloroglucinols Bearing a Lavandulyl-Derived Substituent from Garcinia xanthochymus Fruits. J Nat Prod. 2022 Dec 23;85(12):2845-2855.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1141378-40-6