Products for Research Use Only
RegisterLogin

Dihydro-β-erythroidine (hydrobromide)

CAT: 0804-HY-107670-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107670-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities[1][2][3].
CAS Number
29734-68-7
Product Name Alternative
DHβE (hydrobromide)
UNSPSC
12352005
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dihydro-β-erythroidine-hydrobromide.html
Purity
98.85
Solubility
DMSO : 8 mg/mL (ultrasonic; warming) |H2O : ≥ 100 mg/mL
Smiles
CO[C@@H]1C[C@]23C(CC4=O)=C(CO4)CCN2CCC3=CC1.Br
Molecular Formula
C16H22BrNO3
Molecular Weight
356.25
References & Citations
[1]Harvey SC, et al. Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits. J Neurochem. 1996 Nov;67 (5) :1953-9.|[2]Tabbara RI, et al. Nicotine enhances responding for conditioned reinforcement via α4β2 nicotinic acetylcholine receptors in the ventral tegmental area, but not the nucleus accumbens or the prefrontal cortex. Neuropharmacology. 2019 Apr;148:68-76.|[3]Clementson S, et al. Enantioselective Total Synthesis of (+) -Dihydro-β-erythroidine. J Am Chem Soc. 2019 Jun 5;141 (22) :8783-8786.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N10497Dihydro-β-erythroidine
HY-145119AS-01Mindeudesivir (hydrobromide)
HY-A0009-01Galanthamine (hydrobromide)
HY-125971Xylopropamine (hydrobromide)
HY-113843RETRA (hydrobromide)
HY-N2482A-01Guvacine (hydrobromide)
HY-14806A-01Teneligliptin (hydrobromide)
HY-108723Dihydrogalanthamine (hydrobromide)
HY-18200BAtopaxar (hydrobromide)
HY-W206168-01Tetrahydropapaveroline (hydrobromide)

Alternative Products

CatalogName
B7030-10Dihydro-β-erythroidine hydrobromide
TRC-D452485-5MGDihydro-beta-erythroidine Hydrobromide
BD162627-01Dihydro-b-erythroidine hydrobromide
DXC58250-012- (Decylsulfanyl) -4,5-dihydro-1H-imidazole hydrobromide
OR24108-014,5-Dihydro-2-hydrazino-1H-imidazole hydrobromide
OR961913-012,3-Dihydro-1H-Isoindol-5-ol hydrobromide
CMB68221-015,6-Dihydro-4H-cyclopentathiazol-2-ylamine hydrobromide
OR241062- (Methylthio) -4,5-dihydro-1H-imidazole hydrobromide
0098802,3-Dihydro-imidazo[1,2-a]pyridine Hydrobromide
DXC58601-011- (2-Bromoethyl) -2,3-dihydro-1H-indole hydrobromide

Popular Products