Naphazoline (nitrate) (Standard)

Naphazoline (nitrate) (Standard)

• CAS Number: 5144-52-5
• UNSPSC Description: Naphazoline (nitrate) (Standard) is the analytical standard of Naphazoline (nitrate). This product is intended for research and analytical applications. Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research[1][2].
• Target Antigen: Adrenergic Receptor; Interleukin Related; TNF Receptor; VEGFR
• Type: Reference Standards
• Related Pathways: Apoptosis;GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling;Protein Tyrosine Kinase/RTK
• Field of Research: Inflammation/Immunology; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/naphazoline-nitrate-standard.html
• Smiles: O[N+]([O-])=O.C1(CC2=C3C=CC=CC3=CC=C2)=NCCN1
• Molecular Weight: 273.29
• References & Citations: [1]Quan L, et, al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. Mol Med Rep. 2016 Apr;13(4):3319-25.|[2]Yamaguchi I, et, al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct;203(1):125-31.
• Shipping Conditions: Room temperature