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Naphazoline (nitrate) (Standard)

CAT: 0804-HY-111326AR-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111326AR-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Naphazoline (nitrate) (Standard) is the analytical standard of Naphazoline (nitrate) . This product is intended for research and analytical applications. Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research[1][2].
CAS Number
5144-52-5
Product Name Alternative
Naphthazoline (nitrate) (Standard)
UNSPSC
12352005
Target
Adrenergic Receptor; Interleukin Related; Reference Standards; TNF Receptor; VEGFR
Type
Reference Standards
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/naphazoline-nitrate-standard.html
Smiles
O[N+]([O-])=O.C1(CC2=C3C=CC=CC3=CC=C2)=NCCN1
Molecular Formula
C14H15N3O3
Molecular Weight
273.29
References & Citations
[1]Quan L, et, al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. Mol Med Rep. 2016 Apr;13 (4) :3319-25.|[2]Yamaguchi I, et, al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct;203 (1) :125-31.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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