Propargite

• Description :

  Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM[1]. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC :

  12352005

• Hazard Statement :

  H227-H315-H318-H330-H351-H410

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/propargite.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(OCC#C)OC1C(OC2=CC=C(C(C)(C)C)C=C2)CCCC1

• Molecular Formula :

  C19H26O4S

• Molecular Weight :

  350.47

• Precautions :

  P210-P260-P264-P271-P273-P280-P284-P302+P352-P304+P340-P305+P351+P338-P362+P364-P370+P378-P391-P403-P403+P233-P405-P501

• References & Citations :

  [1]Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9 (1) :4815.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Mite

• CAS Number :

  [2312-35-8]