Propargite

• UNSPSC Description:

  Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM[1]. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/propargite.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(OCC#C)OC1C(OC2=CC=C(C(C)(C)C)C=C2)CCCC1

• Molecular Weight:

  350.47

• References & Citations:

  [1]Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9(1):4815.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2312-35-8