VH032 thiol
CAT:
804-HY-111823-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
VH032 thiol
- CAS Number: 2098836-54-3
- UNSPSC Description: VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].
- Target Antigen: Ligands for E3 Ligase
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-brd4-binding-moiety-3.html
- Purity: 95.91
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)S)NC(C)=O)=O)=O)C=C2
- Molecular Weight: 490.64
- References & Citations: [1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, stored under argon)
- Clinical Information: No Development Reported