(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

• CAS Number: 190315-43-6
• UNSPSC Description: (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2r-3s-4r-2-hydroxymethyl-tetrahydrothiophene-3-4-diol.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1CS[C@H](CO)[C@H]1O
• Molecular Weight: 150.20
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported