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Sodium Camptothecin

CAT: 0804-HY-N8533-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8533-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA[1][2].
CAS Number
25387-67-1
UNSPSC
12352005
Hazard Statement
H301
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sodium-camptothecin.html
Purity
95.0
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=C1N2C(C3=NC4=CC=CC=C4C=C3C2)=CC([C@](CC)(O)C(O[Na])=O)=C1CO
Molecular Formula
C20H17N2NaO5
Molecular Weight
388.35
Precautions
H301
References & Citations
[1]R S Wu, et al. Ribosome formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis. Proc Natl Acad Sci U S A. 1971 Dec;68 (12) :3009-14.|[2]M S Horwitz, et al. Camptothecin: mechanism of inhibition of adenovirus formation. Virology. 1972 Jun;48 (3) :690-8
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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