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Trans-R-138727

CAT: 0804-HY-123669A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-123669A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trans-R-138727 is the trans isomer of R-138727. R-138727 is the active metabolite of the antiplatelet agent Prasugrel (HY-15284). R-138727 is an irreversible inhibitor for the platelet receptor P2Y12, and inhibits ADP-induced platelet activation and aggregation[1].
CAS Number
239466-74-1
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trans-r-138727.html
Purity
98.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C1CN(C(C2=CC=CC=C2F)C(C3CC3)=O)CCC\1S
Molecular Formula
C18H20FNO3S
Molecular Weight
349.42
References & Citations
[1]Hasegawa M, et al. Stereoselective inhibition of human platelet aggregation by R-138727, the active metabolite of CS-747 (prasugrel, LY640315), a novel P2Y12 receptor inhibitor. Thromb Haemost. 2005 Sep;94 (3) :593-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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